journal articles
PERFORMANCE OF A SHORT VERSION OF THE EVERYDAY COGNITION SCALE (ECOG-12) TO DETECT COGNITIVE IMPAIRMENT
M. Manjavong, A. Diaz, M.T. Ashford, A. Aaronson, M.J. Miller, J.M. Kang, S. Mackin, R. Tank, B. Landavazo, D. Truran, S.T. Farias, M. Weiner, R. Nosheny, for the Alzheimer’s Disease Neuroimaging Initiative
J Prev Alz Dis 2024;6(11):1741-1750
BACKGROUND: The Everyday Cognition (ECog) 12-item scale, a functional decline measurement, can distinguish dementia from cognitively unimpaired (CU). Limited data compare ECog-12 performance by raters (self vs. informant) and scoring systems (average numeric vs. categorical grouping) to differentiate cognitive statuses.
OBJECTIVES: To evaluate the performance of ECog-12 in differentiation cognitive statuses.
DESIGN: A cross-sectional diagnostic test study.
SETTING AND PARTICIPANTS: Data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) study are analyzed. Participants were aged 55-90 years old divided into subgroups based on diagnostic criteria.
MEASUREMENTS: We evaluated ECog-12 performance across different diagnostic groups, such as CU vs cognitive impairment (CI; mild cognitive impairment (MCI), and dementia), and the association between ECog-12 and CI. This procedure was repeated for self- and partner (informant)-reports. Additionally, types of ECog scores were also assessed, where an average ECog score was calculated (continuous numeric) as well as a categorical grouping (“any occasional declined” or “any consistently declined”) based on item-level responses to ECog questions.
RESULTS: ECog-12 cut-off scores of 1.36 (self-reported) and 1.45 (partner-reported) distinguish CU from CI with AUC 0.7 and 0.78, respectively. Adding a memory-concern question improved self-reported-ECog AUC to 0.79. Self- and partner-reported “consistently-declined” ECog-12 categorical grouping provided AUC 0.69 and 0.78. The study partner reported ECog-12 showed a greater association with CI than self-reported, with odds ratios of 35.45 and 8.79, respectively.
CONCLUSION: Study partner-reported ECog scores performed better than self-reported ECog-12 in differentiating cognitive statuses, and a higher study partner reported ECog score was a higher prognostic risk for CI. A memory concern question could enhance self-reported ECog-12 performance. This further emphasizes the need to obtain data from study partners for research and clinical practice.
CITATION:
M. Manjavong ; A. Diaz ; M.T. Ashford ; A. Aaronson ; M.J. Miller ; J.M. Kang ; S. Mackin ; R. Tank ; B. Landavazo ; D. Truran ; S.T. Farias ; M. Weiner ; R. Nosheny ; for the Alzheimer’s Disease Neuroimaging Initiative ; (2024): Performance of a Short Version of the Everyday Cognition Scale (ECog-12) to Detect Cognitive Impairment. The Journal of Prevention of Alzheimer’s Disease (JPAD). http://dx.doi.org/10.14283/jpad.2024.109